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Using Propecia may increase your risk of developing prostate cancerYour doctor will perform tests to make sure you do not have other conditions that would prevent you from safely using finasteride.
Significant lethality was observed in male and female mice at single oral doses of 1500 mg/m 2500 mg/kgand in female and male rats at single oral doses of 2360 mg/m 2400 mg/kgand 5900 mg/m 21000 mg/kgrespectively.
Minoxidil was the first drug approved by the FDA for the treatment of male pattern baldnessFor many yearsminoxidilin pill formbrand name Lonitenwas widely used to treat high blood pressureJust like finasterideresearchers discovered a very interesting side effect of the drugPeople taking the medication were growing hair in unexpected placessuch as on their cheeks and the back of their handsSome people grew hair on their foreheads.
Finasteride for male pattern hair loss has been evaluated for safety in clinical studies involving more than 3,200 menIn three 12-monthplacebo-controlleddouble-blindmulticentre studies of comparable designthe overall safety profiles ofPropeciaand placebo were similarDiscontinuation of therapy due to any clinical adverse experience occurred in 1.7of 945 men treated withPropeciaand 2.1of 934 men treated with placebo.
Long-term data on fertility in humans are lackingand specific studies in subfertile men have not been conductedThe male patients who were planning to father a child were initially excluded from clinical trialsAlthoughanimal studies did not show relevant negative effects on fertilityspontaneous reports of infertility andor poor seminal quality were received post-marketingIn some of these reportspatients had other risk factors that might have contributed to infertilityNormalisation or improvement of seminal quality has been reported after discontinuation of finasteride.
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