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Serum protein binding is concentration independent with a bound fraction of approximately 65In a multiple dose study conducted with a research formulation which is less bioavailable than the tablet or suspensionthere was little accumulation of drug in serum or urine after dosing for 14 daysAdequate data on CSF levels of cefixime are not available.
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Antibiotics such as cefixime will not work for coldsfluor other viral infectionsUsing antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.
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resistance in enterococci and listeria monocytogenes may also be related to poor binding of cefixime to the pbps of these organisms.