Deflazacort is a cyp3a4 substrate, diltiazem is a moderate inhibitor of cyp3a4.
Information about Diltiazem.
Diltiazem can increase the levels of certain heart drugs in your bodyThis means that you may have more side effectsThese drugs include:
ChildrenThe safety and effectiveness of diltiazem for use by children have not been established.
Diltiazem may also be used for purposes not listed in this medication guide.
Initial dose30 to 60 mg orally 3 to 4 times a dayMaintenance dose180 to 360 mg orally/day in divided dosesSR initial dose60 to 120 mg orally twice a daySR maintenance dose240 to 360 mg orally/dayCD or XR initial dose120 to 240 mg orally once a dayCD maintenance dose240 to 360 mg orally once a dayXR maintenance dose240 to 480 mg orally once a dayLA initial dose120 to 240 mg orally once a dayLA maintenance dose240 to 420 mg orally once a day.
Kidney functionThe kidneys are partially responsible for removing diltiazem from the bodyAs a resultkidney disease or reduced kidney function may cause this medication to build up in the bodycausing side effectsIf you have reduced kidney function or kidney diseasediscuss with your doctor how this medication may affect your medical conditionhow your medical condition may affect the dosing and effectiveness of this medicationand whether any special monitoring is needed.
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before taking diltiazem, tell your doctor if you are allergic to any drugs, or if you have kidney disease, liver disease, or congestive heart failure.