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Letrozole is a medication that is metabolized rapidly in the bodyIt is not thought to have significant levels in the blood or tissues for a prolonged period of time.

Letrozole was first approved by the U.SFood and Drug AdministrationFDAon October 292004for extended adjuvant treatmentand a year after the approval was extended by the FDA for the drug to be used as an initial adjuvant treatmentIt is commercialized under the brand name femara by Novartis Pharmaceuticals Corpand it is currently approved for postmenopausal women diagnosed with hormone-receptor-positiveearly-stage breast cancer right after surgeryor possibly chemotherapy and radiationto reduce the risk of the cancer coming backpostmenopausal women diagnosed with hormone-receptor-positive early-stage breast cancer who have taken 5 years of tamoxifen to reduce the risk of the cancer coming backor postmenopausal women diagnosed with advanced-stage or metastatic hormone-receptor-positive breast cancer.

Letrozole is available through retail or mail order pharmacyYour oncology team will work with your prescription drug plan to identify an in-networkretail or mail order pharmacy for medication distribution.

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