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2For treatment of female hypoestrogenism due to hypogonadismcastrationor primary ovarian failure.
24Cohen LCoxwell WLMelchione TKoltun WGibson EGupta NRoberts MLow-dose 17-beta estradiol matrix transdermal system in the treatment of moderate-to-severe hot flushes in postmenopausal womenCurr Ther Res Clin Exp 601999534-47.
Long term continuous administration of natural and synthetic estrogens in certain animal species increases the frequency of carcinomas of the breastuteruscervixvaginatestisand liver.
A total of 280 drugs1112 brand and generic namesare known to interact with Estraceestradiol
There arehoweverpossible risks which may be associated with the use of progestins with estrogens compared to estrogen-alone regimensThese include a possible increased risk of breast cancer.
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