Some doses of celebrex should be taken with food.
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Liver and biliaryHepatic enzyme increasedincluding SGOT increasedSGPT increased)
Inhibition of PGE2 synthesis may lead to sodium and water retention through increased reabsorption in the renal medullary thick ascending loop of Henle and perhaps other segments of the distal nephronIn the collecting ductsPGE2 appears to inhibit water reabsorption by counteracting the action of antidiuretic hormone.
GeneralHypersensitivityallergic reactionchest paincyst NOSedema generalizedface edemafatiguefeverhot flushesinfluenza-like symptomspainperipheral pain.
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celebrex has demonstrated significant reduction in joint pain compared to placebo.
