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Apo-dipyridamole inhibits the uptake of adenosine into platelets, endothelial cells and erythrocytes in vitro and in vivo , the inhibition occurs in a dose-dependent manner at therapeutic concentrations 0.

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Dipyridamole may cause side effectsTell your doctor if any of these symptoms are severe or do not go away:

In case of real or suspected overdoseseek medical attention or contact a Poison Control Center immediatelyCareful medical management is essentialBased upon the known hemodynamic effects of dipyridamolesymptoms such as warm feelingflushessweatingrestlessnessfeeling of weakness and dizziness may occurA drop in blood pressure and tachycardia might also be observed.

Following an oral dose of Persantinedipyridamoletabletsthe average time to peak concentration is about 75 minutesThe decline in plasma concentration following a dose of Persantinedipyridamoletablets fits a two-compartment modelThe alpha half-lifethe initial decline following peak concentrationis approximately 40 minutesThe beta half-lifethe terminal decline in plasma concentrationis approximately 10 hoursDipyridamole is highly bound to plasma proteinsIt is metabolized in the liver where it is conjugated as a glucuronide and excreted with the bile.

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dipyridamole by injection should not be used if you have an allergy to dipyridamole, or any of its ingredients certain heart problems including abnormal heart beat, electrical conduction problems second or third degree atrioventricular block , abnormal heart rhythm sick sinus syndrome , unstable angina pectoris, severe coronary artery disease, recently had a heart attack myocardial infarction or have heart failure recently had a stroke low blood pressure hypotension myasthenia gravis a rare disease with muscle weakness blood clotting coagulation disorders bronchial asthma, or tendency to bronchospasm recent, unexplained fainting.

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