It, like the c act as agonists at some and antagonists at best-studied serm, tamoxifen, has estrogen agonist other ers properties in some tissues and estrogen antagonism 2.
Information about Tamoxifen.
Tamoxifen is prescribed to treat metastatic breast canceror cancer that has spread to other parts of the bodyTamoxifen is also used to lower the chance of breast cancer in high-risk womenfor examplethose with a family history of breast cancer
This list is not complete and other drugs may interact with tamoxifenNolvadexTell your doctor about all medications you useThis includes prescription and over-the-counterOTCdrugsvitamin and herbal productsand recreational drugsDo not start a new medication without telling your doctor.
AThe results of therapy with any drug can be both positive and negative and it is always important to weight the potential benefits against the potential risks of treatmentDepending on your diagnosisand reason for taking tamoxifenthe benefits may be well provenYou should discuss these with your healthcare provider to have a full understanding of them and then evaluate them against the risksAccording to the package inserttamoxifen is generally well toleratedwith the most common side effects being hot flashesvaginal dryness and a mild vaginal dischargeThe risk of more serious side effects has been evaluated in scientific studiesOver a period of nearly 7 yearsthe risk of uterine cancer in people taking tamoxifen is approximately 2 per 1,000 women-yearsThe risk of blood clotsincluding stroke and pulmonary embolismis about 1-1.5 per 1,000 women-yearsFor more informationplease contact your healthcare providerMichelle McDermottPharmD.
In 2006an FDA advisory panel recommended that a more specific warning label about its side effects be added to tamoxifen
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