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Kytril contains the active ingredient granisetron.

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During clinical trials325 patients 65 years of age or older received KYTRILgranisetronTablets298 were 65 to 74 years of ageand 27 were 75 years of age or olderEfficacy and safety were maintained with increasing age.

It is not known whether granisetron is excreted in human milkBecause many drugs are excreted in human milkcaution should be exercised when KYTRILgranisetronis administered to a nursing woman.

STORAGEFor oral tabletsStore at room temperature between 59-86 degrees F15-30 degrees CFor oral solutionStore at room temperature at 77 degrees F25 degrees CBrief storage between 59-86 degrees F15-30 degrees Cis permittedStore bottle in an upright position.Store away from light and moistureDo not store in the bathroomKeep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do soProperly discard this product when it is expired or no longer neededConsult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Granisetron does not induce or inhibit the cytochrome P-450 drug-metabolizing enzyme system in vitroThere have been no definitive drug-drug interaction studies to examine pharmacokinetic or pharmacodynamic interaction with other drugshoweverin humansKYTRILgranisetronInjection has been safely administered with drugs representing benzodiazepinesneurolepticsand anti-ulcer medications commonly prescribed with antiemetic treatmentsKYTRILgranisetronInjection also does not appear to interact with emetogenic cancer chemotherapiesBecause granisetron is metabolized by hepatic cytochrome P-450 drug-metabolizing enzymesinducers or inhibitors of these enzymes may change the clearance andhencethe half-life of granisetronNo specific interaction studies have been conducted in anesthetized patientsIn additionthe activity of the cytochrome P-450 subfamily 3A4involved in the metabolism of some of the main narcotic analgesic agentsis not modified by KYTRILgranisetronin vitro.

An electrolyte imbalancesuch as low levels of potassium or magnesium in your bloodor.

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