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Patients may experience side effects during administration of cyclophosphamideThese side effects may include hot flushesdizzinessa strange tasterunny eyes and a feeling of having a blocked nosePatients should tell their healthcare provider if they experience any of these symptoms during administration of cyclophosphamideOnce cyclophosphamide is administeredit is eliminated from the body through the kidneys.

Nervous Systemencephalopathyconvulsiondizzinessneurotoxicity has been reported and manifested as reversible posterior leukoencephalopathy syndromemyelopathyperipheral neuropathypolyneuropathyneuralgiadysesthesiahypoesthesiaparesthesiatremordysgeusiahypogeusiaparosmia.

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DUse in LIFE-THREATENING emergencies when no safer drug availablePositive evidence of human fetal risk.

EtanerceptIn patients with Wegener’s granulomatosisthe addition of etanercept to standard treatmentincluding cyclophosphamidewas associated with a higher incidence of non-cutaneous malignant solid tumors.

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