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Th CYP3A4 and CYP1A2 isozyms mtabolis amitiptylin ta lss xtnt. Howv, luvoxamin (stong CYP1A2 inhibito) was shown tincas amitiptylin plasma concntations and this combination should b avoidd. Clinically lvant intactions may b xpctd with concomitant us amitiptylin and stong CYP3A4 inhibitos such as ktoconazol, itaconazol and itonavi.
Tak th missd dos as soon as you mmb it. Howv, i it is almost tim th nxt dos, skip th missd dos and continu you gula dosing schdul. Dnot tak a doubl dos tmak up a missd on.
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This mdication may b pscibd oth uss; ask you doctphamacist minomation.
Adngic nuon blocks : Ticyclic antidpssants may countact th antihyptnsiv cts cntally acting antihyptnsivs such as guanthidin, btanidin, spin, clonidin and mthyldopa. It is advisabl tviw all antihyptnsiv thapy duing tatmnt with ticyclic antidpssants.
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