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The plasma half-life of labetalol following oral administration is about 6 to 8 hoursSteady-state plasma levels of labetalol during repetitive dosing are reached by about the third day of dosingIn patients with decreased hepatic or renal functionthe elimination half-life of labetalol is not alteredhoweverthe relative bioavailability in hepatically impaired patients is increased due to decreasedfirst-passmetabolism.<\/p>\n
The antianginal efficacy of labetalol HCl has not been studiedIn 37 patients with hypertension and coronary artery diseaselabetalol HCl did not increase the incidence or severity of angina attacks.<\/p>\n
Use this medication regularly to get the most benefit from itTo help you remembertake it at the same times each day.<\/p>\n
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