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The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including nonsteroidal antiinflammatory agents and other drugs that are highly protein boundsalicylatessulfonamideschloramphenicolprobenecidcoumarinsmonoamine oxidase inhibitorsand beta adrenergic blocking agentsWhen such drugs are administered to a patient receiving MICRONASEthe patient should be observed closely for hypoglycemiaWhen such drugs are withdrawn from a patient receiving MICRONASEthe patient should be observed closely for loss of control.<\/p>\n

The effectiveness of any hypoglycemic drugincluding MICRONASEin lowering blood glucose to a desired level decreases in many patients over a period of time which may be due to progression of the severity of diabetes or to diminished responsiveness to the drugThis phenomenon is known as secondary failureto distinguish it from primary failure in which the drug is ineffective in an individual patient when MICRONASE is first givenAdequate adjustment of dose and adherence to diet should be assessed before classifying a patient as a secondary failure.<\/p>\n

NoDiabeta does not have a generic glyburide counterpartIf your doctor writes a prescription for Diabetait MUST be dispensed as Diabeta.<\/p>\n

During pregnancythis medication should be used only when clearly neededPregnancy may cause or worsen diabetesDiscuss a plan with your doctor for managing your blood sugar while pregnantYour doctor may substitute insulin for this drug during pregnancyIf glyburide is usedit may be switched to insulin at least 2 weeks before the expected delivery date because of glyburide’s risk of causing low blood sugar in your newbornDiscuss the risks and benefits with your doctor.<\/p>\n

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as you may already know, there are two different forms of glyburide, regular nonmicronized glyburide micronase, diabeta and micronized glyburide glynase that can t be substituted for each other.