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When intranasal corticosteroids are used at higher than recommended dosages or in susceptible individuals at recommended dosagessystemic corticosteroid effects such as hypercorticism and adrenal suppression may appearIf such changes occurthe dosage of FLONASE Nasal Spray should be discontinued slowly consistent with accepted procedures for discontinuing oral corticosteroid therapy.<\/p>\n

Flonase Nasal Spray1 or 2 sprays50 mcg\/sprayin each nostril once a day as neededAfter 6 months of daily use ask your doctor if you can keep using this medicine.<\/p>\n

Do not use this bottle for more than the labeled number of sprays even though the bottle is not completely emptyBefore you throw the bottle awayyou should talk to your healthcare provider to see if a refill is neededDo not take extra doses or stop taking FLONASE Nasal Spray without talking to your healthcare provider.<\/p>\n

The use of strong cytochrome P450 3A4CYP3A4inhibitorse.gritonaviratazanavirclarithromycinindinaviritraconazolenefazodonenelfinavirsaquinavirketoconazoletelithromycinconivaptanlopinavirnefazodonevoriconazolewith FLONASE Nasal Spray is not recommended because increased systemic corticosteroid adverse effects may occursee DRUG INTERACTIONSCLINICAL PHARMACOLOGY<\/p>\n

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