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Other than for use in the treatment of giardiasis and amebiasis in pediatric patients older than three years of agesafety and effectiveness of tinidazole in pediatric patients have not been established.

There are no reported overdoses with tinidazole in humansIn acute studies with mice and ratsthe LD 50 for mice was generally3,600 mg/kg for oral administration and was2,300 mg/kg for intraperitoneal administrationIn ratsthe LD 50 was2,000 mg/kg for both oral and intraperitoneal administration.

Metronidazolea chemically-related nitroimidazolehas been reported to be carcinogenic in mice and rats but not hamstersIn several studies metronidazole showed evidence of pulmonaryhepaticand lymphatic tumorigenesis in mice and mammary and hepatic tumors in female ratsTinidazole carcinogenicity studies in ratsmice or hamsters have not been reported.

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the dose regimen differs depending on what you are taking it for so, if unsure, you should confirm what your tinidazole prescription is for.

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The plasma half-life of tinidazole is approximately 12-14 hoursTinidazole is excreted by the liver and the kidneysTinidazole is excreted in the urine mainly as unchanged drugapproximately 20-25of the administered doseApproximately 12of the drug is excreted in the feces.

Before you take tinidazoletell your doctor if you have kidney diseaseor if you are on dialysisepilepsy or other seizure disordera blood cell disorder such as anemia or low plateletsor a weak immune system.

Tinidazole is a synthetic antiprotozoal and antibacterial agentIt is 12ethylsulfonyl)ethyl2-methyl5-nitroimidazolea second-generation 2-methyl-5-nitroimidazolewhich has the following chemical structure:

Tinidazole may cause side effectsTell your doctor if any of these symptoms are severe or do not go away:

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all subjects received a single oral dose of 2 g four 500 mg tablets of tinidazole following an overnight fast.