Information about Methotrexate.

A 5mg folate tablet taken the day after your Methotrexate dose is the recommended treatment to manage these side effectsFolate tablets in 5mg strength can be purchased over the counter in most pharmacies.

Methotrexate self-injectable solution can interact with other medicationsvitaminsor herbs you may be takingAn interaction is when a substance changes the way a drug worksThis can be harmful or prevent the drug from working well.

Do not take these drugs with methotrexateWhen used with methotrexatethese drugs can cause dangerous effects in your bodyExamples of these drugs include:

Maintenanceduring remission15 mg/m2 IM or orally twice a weekAlternate remission dosing2.5 mg/kg IV every 14 days.

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unexpectedly severe, sometimes fatal gastrointestinal toxicity and gi bleeding have been reported with concomitant administration of methotrexate usually in high dosage and some nonsteroidal anti-inflammatory drugs nsaids .

Information about Methotrexate.

Take methotrexate exactly as it was prescribed for you Follow all directions on your prescription label and read all medication guides or instruction sheets.

This medicine can pass into body fluidsurinefecesvomitCaregivers should wear rubber gloves while cleaning up a patient’s body fluidshandling contaminated trash or laundry or changing diapersWash hands before and after removing glovesWash soiled clothing and linens separately from other laundry.

Methotrexate is used to treat certain types of cancer of the breastskinhead and neckor lungIt is also used to treat severe psoriasis and rheumatoid arthritis.

Methotrexate self-injectable solution can interact with other medicationsvitaminsor herbs you may be takingAn interaction is when a substance changes the way a drug worksThis can be harmful or prevent the drug from working well.

This is not a complete list of side effects and others may occurCall your doctor for medical advice about side effectsYou may report side effects to FDA at 1-800-FDA-1088.

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normal dividing cells preferentially absorb leucovorin, hence, it decreases the action of methotrexate, thereby decreasing methotrexate s adverse systemic effects.