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O hot flashesshort periods of feeling warm and sweatingo body painincluding backpelvisstomacho feeling weak o constipation o infection o nausea o swelling in your armsankleslegs or feet o shortness of breathdyspneao dizziness o diarrhea o blood in your urine o frequent urination at night o a decrease in red blood cellsanemia)

Before using this medicationtell your doctor or pharmacist your medical historyespecially ofliver diseasediabetesheart disease.

Based on animal studiesCasodex can lead to inhibition of spermatogenesis and may impair fertility in males of reproductive potentialThe long-term effects of Casodex on male fertility have not been studiedsee Nonclinical Toxicology13.1

Do not stop taking any medications without consulting your healthcare provider.

9Nieh PTWithdrawal phenomenon with the antiandrogen casodexJ Urol 15319951070-2;disc1072-3.

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casodex bicalutamide is an anti-androgen.

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5Newling DWThe response of advanced prostatic cancer to a new non-steroidal antiandrogenresults of a multicenter open phase II study of CasodexEuropean/Australian Co-operative GroupEur Urol 18 Suppl 3199018-21.

Dermatologic side effects including rash and sweating have been reportedRef]

In vitro protein binding studies have shown that bicalutamide can displace coumarin anticoagulants from binding sitesPT/INR should be closely monitored in patients concomitantly receiving coumarin anticoagulants and CasodexAdjustment of the anticoagulant dose may be necessarysee Warnings and Precautions5.2and Adverse Reactions6.2

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pediatric use the safety and effectiveness of casodex bicalutamide in pediatric patients have not been established.