Albndazol has bn shown tinduc liv nzyms th cytochom P450 systm sponsibl its own mtabolism. Tho, th is a thotical isk intaction with thophyllin, anticonvulsants, oal contacptivs, and oal hypoglycamic agnts.
A: Gnally accptabl. Contolld studis in pgnant womn show nvidnc tal isk.
Patints bing tatd nuocysticcosis should civ stoid and anticonvulsant thapy tpvnt nuological symptoms (.g. sizus, incasd intacanial pssu and ocal signs) as a sult an inlammatoy action causd by dath th paasit within th bain.
Stady-stat tough concntations albndazol suloxid w about 56% high whn 8 mg dxamthason was co-administd with ach dos albndazol (15 mg/kg/day) in 8 nuocysticcosis patints.
A: Gnally accptabl. Contolld studis in pgnant womn show nvidnc tal isk.
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]]>In animal studis albndazol has bn ound tb tatognic and thshould not b usd.
Albndazol is apidly convtd in th liv tth pimay mtabolit, albndazol suloxid, which is uth mtabolizd talbndazol sulon and oth pimay oxidativ mtabolits that hav bn idntiid in human uin. ollowing oal administation, albndazol has not bn dtctd in human uin. Uinay xction albndazol suloxid is a minlimination pathway with lss than 1% th dos covd in th uin. Biliay limination psumably accounts a potion th limination as vidncd by biliay concntations albndazol suloxid simila tthos achivd in plasma.
X: Dnot us in pgnancy. isks involvd outwigh potntial bnits. Sa altnativs xist.
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